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Epigenetic pacemaker (Sciuridae)

Subcategory: molecular aging
Standard reference: Snir et al. and other EPM references cited
Papers: 1 | Mentions: 2

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Knowledge graph centered on Epigenetic pacemaker (Sciuridae) with 15 nodes and 27 connections. Top connected: mark-recapture (Sciuridae), winter survival, Hibernation slows epigenetic ageing in yellow-bell, epigenetic clock, DNA methylation.

Description

Development of species-specific epigenetic clocks using cross-mammalian methylation arrays and elastic-net penalized regression to predict chronological age from DNA methylation patterns.

Typical Equipment

  • Qiagen DNeasy blood and tissue kit
  • NanoDrop
  • Infinium EPIC array
  • mammalian methylation array probes
  • R software

Output Measurements

  • epigenetic age
  • chronological age prediction
  • methylation levels

Papers Using This Protocol (1)

article

Hibernation slows epigenetic ageing in yellow-bellied marmots

2022Nature Ecology & Evolutionusing